Category Archive: Bioinformatics

Aug 20

Three-Dimensional (3D) Printing: A Gateway to Precision Cancer Medicine

Researchers are using 3D printing to gain insights that contribute to advances in basic biomedical research and the development of precision medical therapies by creating 3D models of pathogens, tumors, normal tissues, cells, and biomolecules. Dr. Sriram Subramaniam, principal investigator in the Laboratory of Cell Biology at the NCI Center for Cancer Research (CCR), uses …

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Permanent link to this article: http://ncip.nci.nih.gov/blog/three-dimensional-3d-printing-gateway-precision-cancer-medicine/

Aug 19

NCIP Hub: Addressing Imaging Community Needs

In his earlier post, Ishwar Chandramouliswaran introduced the objectives of the NCIP Hub, an online resource for research and collaboration in cancer informatics. As a scientific repository, the NCIP Hub can store community-generated data, tools, and other resources. Members can upload tools, conduct analyses, and collaborate, giving researchers the opportunity to engage with and leverage …

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Permanent link to this article: http://ncip.nci.nih.gov/blog/ncip-hub-addressing-imaging-community-needs/

May 12

NCIP Hub: A Platform for Scientific Collaboration, Resource Sharing, and Education

One of the major goals of the NCIP is to help facilitate open innovation and scientific collaboration in the cancer research and informatics community.  To that end, we have undertaken several projects, two of which were the focus of previous NCIP blog posts:  The Cancer Genomics Cloud Pilot, an initiative to democratize access to and …

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Permanent link to this article: http://ncip.nci.nih.gov/blog/ncip-hub-platform-scientific-collaboration-resource-sharing-education/

May 02

Dr. George Komatsoulis, CBIIT Deputy Director, Leaving the NCI

To the Cancer Informatics Community, As you may know, Dr. George Komatsoulis, Deputy Director of the NCI Center for Biomedical Informatics and Information Technology (CBIIT), will be leaving the NCI on May 2, 2014 to join the National Center for Biotechnology Information (NCBI) at the National Library of Medicine, where he will be focusing on …

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Permanent link to this article: http://ncip.nci.nih.gov/blog/dr-george-komatsoulis-cbiit-deputy-director-leaving-nci/

Jan 27

Winning an HPN-DREAM8 Challenge: Competition and Collaboration Supporting Open Scientific Research and Development

While working with big genomics data can be very challenging, it can also be fun. And when your team wins a competition, it’s positively exhilarating, as our NCIP Computational Genomics Research Group discovered while participating in the 8th annual set of challenges posed by The Dialogue on Reverse Engineering Assessment and Methods (DREAM) project. DREAM …

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Permanent link to this article: http://ncip.nci.nih.gov/blog/winning-hpn-dream8-challenge-competition-collaboration-supporting-open-scientific-research-development/

Sep 27

NCI’s CPTAC Releases an Openly Accessible Data Set Primed for Multi-omic Integration

On September 4, 2013, NCI’s Clinical Proteomics Tumor Analysis Consortium (CPTAC) publicly released proteomic data produced from colorectal tumor samples previously analyzed as part of The Cancer Genome Atlas (TCGA) initiative.  This is the first release of proteomic tumor data designed to complement genomic data from the same tumors. Since its launch in 2006, the …

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Permanent link to this article: http://ncip.nci.nih.gov/blog/ncis-clinical-proteomic-tumor-analysis-consortium-releases-openly-accessible-data-set-primed-multi-omic-integration/

Sep 09

The Future of the Pathway Interaction Database (PID) — A Conversation with Dr. Daoud Meerzaman

The Pathway Interaction Database (PID) is a collection of biomolecular interactions and events involving signaling and regulatory pathways that have been curated from the peer-reviewed literature. Users are able to browse through biomolecular interactions, run computational analyses, or synthesize and combine interactions to establish novel pathways. Begun as a collaborative project between the National Cancer …

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Permanent link to this article: http://ncip.nci.nih.gov/blog/future-pathway-interaction-database-pid-conversation-dr-daoud-meerzaman/

Aug 28

Reducing Friction: An Update on the NCIP Open Development Initiative

I was fortunate enough to attend the Bioinformatics Open Source Conference (BOSC) this summer and heard a wonderful talk by Cameron Neylon on “The Role of Open Source and Open Thinking.”  In his talk, he presented a clever equation for calculating the probability of helping someone through an open source project: P (of helping someone) …

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Permanent link to this article: http://ncip.nci.nih.gov/blog/reducing-friction-an-update-on-the-ncip-open-development-initiative/

Jul 10

NCI Board of Scientific Advisors Approves NCI Cancer Genomics Cloud Concept

In a series of previous blog posts, Juli Klemm and I discussed the challenges associated with the growth of biomedical research data, and the results of an informal survey of computational limitations currently experienced by biomedical researchers. One possible solution to resolving these challenges is what we are calling a “cancer genomics cloud,” a computing …

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Permanent link to this article: http://ncip.nci.nih.gov/blog/nci-board-of-scientific-advisors-approves-nci-cancer-genomics-cloud-concept/

May 31

Input on Cancer Knowledge Clouds: Key Themes from the Community

    “We cannot solve our problems with the same thinking we used when we created them.” — Albert Einstein There is no shortage of reports describing the informatics challenges presented by the massive data volumes generated by today’s genomics technologies, particularly ultra high-throughput sequencing.  The facility with which these data can be generated has the …

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Permanent link to this article: http://ncip.nci.nih.gov/blog/input-on-cancer-knowledge-clouds-key-themes-from-the-community/

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