Category: genomics

Sep 25

NCI’s Office of Data Sharing: Setting a “Gold” Standard for Childhood Cancer

Jaime M. Guidry Auvil headshot (A woman with shoulder length brown hair in a gray suit jacket with a white collar) on a white and blue background

By Jaime M. Guidry Auvil, Ph.D. Director, Office of Data Sharing Center for Biomedical Informatics and Information Technology Dr. Jaime M. Guidry Auvil serves as the director of the newly-launched NCI Office of Data Sharing (ODS). Headquartered at the Center for Biomedical Informatics and Information Technology, ODS is creating a comprehensive data sharing vision and …

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Permanent link to this article: https://ncip.nci.nih.gov/blog/ncis-office-data-sharing-setting-gold-standard-childhood-cancer/

Sep 20

The Promise and the Challenge of Deep Learning in Pathology

Lee Cooper's headshot: A man standing in front of trees with a white shirt and black suit jacket on a blue and white background.

By Lee Cooper, Ph.D. Assistant Professor, Department of Biomedical Informatics Emory University School of Medicine Assistant Professor, Wallace H. Coulter Department of Biomedical Engineering Georgia Institute of Technology and Emory University One of the most exciting developments of the past decade has been the success of methods broadly described as deep learning. While the roots …

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Permanent link to this article: https://ncip.nci.nih.gov/blog/promise-challenge-deep-learning-pathology/

Aug 08

Predictive Modeling for Pre-clinical Drug Screening: Improving Models Derived From Observational Studies Using Machine Learning and Simulation

Authors: Jim Doroshow, M.D., Yvonne A. Evrard, Ph.D., and Rick Stevens

This blog post, the fifth, concludes our series that discusses the principles underlying the collaborative project “Joint Design of Advanced Computing Solutions for Cancer (JDACS4C).” Investigators from the National Cancer Institute (NCI) and the Frederick National Laboratory for Cancer Research have been working collaboratively with experts in applied machine learning and computer science using the …

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Permanent link to this article: https://ncip.nci.nih.gov/blog/predictive-modeling-pre-clinical-drug-screening-improving-models-derived-observational-studies-using-machine-learning-simulation/

Jan 17

Artificial Intelligence in Cancer Diagnostics and Prognostics: Radiologists in the Driver’s Seat

Hugo Aerts, Ph.D.Hugo Aerts, Ph.D.

By Hugo Aerts, Ph.D. Director, Computational Imaging and Bioinformatics Laboratory (CIBL) Associate Professor, Harvard University In the past year, the use of Artificial Intelligence (AI) in radiology, also called “radiomics,” has been getting a lot of attention, mainly because of the progress Deep Learning (DL) has made from a sub-human performance to performance that is …

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Permanent link to this article: https://ncip.nci.nih.gov/blog/artificial-intelligence-cancer-diagnostics-prognostics-radiologists-drivers-seat/

Jan 03

Breaking Down Data Silos: The Urgency of Now

By NCI Center for Biomedical Informatics and Information Technology (CBIIT) and Center for Strategic Scientific Initiatives (CSSI) Staff Now is the time for researchers across domains to ideate together, share data, and maximize the utility of those data. This is “the urgency of now” according to former Vice President Joe Biden, who delivered the keynote …

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Permanent link to this article: https://ncip.nci.nih.gov/blog/breaking-data-silos-urgency-now/

Mar 07

Democratizing Access to CCG Data: Cancer Genomics Cloud Pilots

By Izumi Hinkson, Ph.D., NCI CBIIT Cancer Informatics Branch In recent years, genomics has been described as a big data science on par with the likes of Twitter, YouTube, and the scientific pursuit of understanding the universe1. These comparisons are certainly not exaggerations, especially considering that genomic data is generated at a rate of 1 zetta-bases …

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Permanent link to this article: https://ncip.nci.nih.gov/blog/democratizing-access-ccg-data-cancer-genomics-cloud-pilots/

Oct 31

The Real Value of an Atlas

Trey Ideker

By Trey Ideker, Ph.D., Director, San Diego Center for Systems Biology, University of California San Diego, Department of Medicine These days there seems to be a lot of talk about atlases for cancer. Most of us are familiar with The Cancer Genome Atlas (TCGA), the long-running effort which, over the past decade, sequenced genomes from …

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Permanent link to this article: https://ncip.nci.nih.gov/blog/real-value-atlas/

Aug 29

Cancer Genomics Cloud Pilots DREAM Challenge — Leveraging the Wisdom of the Crowd

Anthony Kerlavage, Ph.D.Tony Kerlavage, Ph.D.

By Tony Kerlavage, Ph.D., NCI CBIIT, Cancer Informatics Branch In recent years, Challenges have become a popular way to engage and motivate the research and innovation communities to solve difficult problems. Challenges are open competitions where communities are presented with specific and often difficult problems to solve. Participants are given guidelines and test data, and …

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Permanent link to this article: https://ncip.nci.nih.gov/blog/cancer-genomics-cloud-pilots-dream-challenge-leveraging-wisdom-crowd/

Jun 14

Learn more about the Genomic Data Commons

NCI has launched the Genomic Data Commons (GDC), a system that will promote sharing of genomic and clinical data between researchers and facilitate precision medicine in oncology. The GDC was created to centralize, standardize, and broaden access to data from NCI programs such as The Cancer Genome Atlas (TCGA) and its pediatric equivalent, Therapeutically Applicable …

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Permanent link to this article: https://ncip.nci.nih.gov/blog/genomic-data-commons-launched/

May 11

Collaborating Against Cancer: Inter-Agency Pilots

“We are on the cusp of breakthroughs that will save lives, benefit all of humanity. But we have to work together.” Vice President Joe Biden’s words at the American Association for Cancer Research conference resonate as a clear call to action. When we collaborate and share our expertise, the cancer informatics community can bring a …

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Permanent link to this article: https://ncip.nci.nih.gov/blog/collaborating-cancer-inter-agency-pilots/