Sep 07

NCIP News Update, September 7, 2012

Two heads with informatics cloudWelcome to NCIP News Update, our regularly reoccuring blog post of NCIP news and information. Please check in regularly to receive details about NCIP as we continue to evolve this new program. Links to these updates will also be published via the @NCI_NCIP Twitter account, the NCIP Announce listserv, and the NCIP LinkedIn Group. As always, your feedback is welcome!


New Release:  caAERS Version 2.5 Release

NCI CBIIT is pleased to announce the availability of Version 2.5 of the Cancer Adverse Event Reporting System (caAERS). The system is freely available at caAERS is an open source software tool that is used to record and report adverse events that occur during clinical trials. This tool supports regulatory and protocol compliance for adverse event reporting and allows local collection, management, and querying of adverse event data. caAERS also supports service-based integration of data from other clinical trials management systems.

Version 2.5 of caAERS includes the following enhancements:

Complete, automated integration with the NCI Cancer Therapy Evaluation Program Enterprise System (CTEP-ESYS) for protocol abstractions and supporting data that is needed for expedited adverse event reporting to the NCI CTEP.

  • NCI CTEP-approved support for electronic, expedited report submissions from caAERS to the CTEP Adverse Event Expedited Reporting System (AdEERS).
  • Expansion of the number of service-based APIs for automated data entry into the system from five to fourteen.

For questions about caAERS or clinical trials support capabilities, please visit the NCI Wiki: or the NCI Clinical Tools Discussion Forum: for end users; and for developers.


New Release:  caNanoLab 1.5.4

We are also pleased to announce the release of caNanoLab 1.5.4 and the deployment of the system at NCI CBIIT,  This minor release contains a number of small bug fixes and technical enhancements.

For a complete list of items addressed in this release and known issues, see the Release Notes, .

The installation guide and additional information about caNanoLab is available on the project wiki,

Please contact NCI CBIIT Application Support for additional information and technical assistance,


 Publication of the ENCODE Project

The big news in genomic research this week is the publication of the ENCODE project.

ENCODE, the Encyclopedia of DNA Elements, is a project funded by the National Human Genome Research Institute to identify all regions of transcription, transcription factor association, chromatin structure and histone modification in the human genome sequence. Thanks to the identification of these functional elements, 80% of the components of the human genome now have at least one biochemical function associated with them. This expansive resource of functional annotations is already providing new insights into the organization and regulation of our genes and genome.

Thirty papers were published simultaneously across three journals, and Nature has made available a tool to help navigate them. The following is from
The researchers and publishers developed a new digital tool featuring 13 ‘threads’, each on a different topic, pulling together information from all the disparate papers and allowing the reader to view it in a single stream of text. Nature’s editorial likens the tool to an automated “highlighter pen,” sifting through the pages of information, picking out relevant paragraphs for the reader’s interest. The web of threads is freely accessible on Nature’s website and is also available as a free iPad app.


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1 comment

  1. I really appreciate the great work being done on this blog, Kudos!

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